I have 100mg tartrate & 100mg succinate = can I interchange these on a daily basis? I am to take 100mg twice a day
NO. The tartrate is short acting. You really can't take it every 12 hrs. It needs to be closer together.
the succinate is long acting and can be taken every 12 hrs.
What I'm about to say is NOT medical advice as I have no authority to give it, but the confusion between metoprolol tartrate and metoprolol succinate can be answered by what my doctor and pharmacist have told me.
The difference is that Metoprolol SUCCINATE slow-releases its dose over a 24-hour period, whereas, Metoprolol TARTRATE releases over a 12-hour period, .. so you can either take your entire daily dose, as succinate, once a day, .. or .. you can take tartrate twice a day with each dose being half of the total daily milligrams you need.
The main thing is that you must be TOTALLY CLEAR from your doctor as to how many total milligrams you're supposed to take per day. I've never heard of anyone taking 200 milligrams per day, but as I said, I'm not a doctor, so my only concern is that you make sure ( from your doctor ) as to what your total daily dose should be.
My doctor has me on a total of 50mg per day, so I can take it either as a 25mg "tartrate" pill TWICE a day .. or as a 50mg "succinate" pill ONCE a day.
The only advantage of "tartrate" is that it's usually a little less expensive than succinate; but since tartrate lasts only 12 hours, it's double the hassle (especially since you're supposed to take it with food to slow down the absorption rate), so you have to take it (with food) twice a day. According to my pharmacist, there are two advantages of metoprolol succinate over the tartrate: 1) Since succinate dispenses into your body over a 24-hour period, you only need to schedule to take it once a day, .. and 2) succinate dispenses more slowly and evenly, so fewer people tend to experience any short-term side effects as they might with the faster-acting form.
According to my semi-educated understanding of Metroprolol "tartrate" and "succinate", if I had to take 200mg a day, I would take my full daily amount as succinate, so I would only have to take it once a day. But if succinate is too expensive, then I would take a 100mg pill of the tartrate every twelve (12) hours.
Since 12-hour-release pills "peak" higher and "dip" lower in your system than 24-hour-release pills, I personally would NOT interchange tartrate and succinate any more frequently than I had to, especially not on a daily basis; .. but if I had to, I wouldn't have a problem switching from tartrate to succinate (12 hours after taking my last tartrate) .. or from succinate to tartrate (24 hours after taking my last succinate).
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