The half life of Methylprednisolone varies from 1.8 to 5.2 hours. This is the time it takes for the drug levels in your plasma to reduce by half.
For a drug to be totally eliminated from your system it takes around 5.5 times the half life.
As an estimate then, after taking a dose of Methylprednisolone it should be out of your system after 28 hours (just over a day).
However other factors to consider include:
1. How much and how often you have taken the drug.
2. Your metabolic rate – a slower metabolism will increase the time a drug remains in your system.
3. Your age and health – older age and poor health will generally increase the time the drug stays in your system.
4. Body mass – generally the bigger you are the longer a drug will remain in your system.
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