I'm 54 and currently taking 20mg a week but am thinking of asking Dr if I can increase it. I started this Rx 9/2015 when I couldn't even sleep due to severe pains and it works, for the most part, with no side effects. It's now only slight pains in a knuckle and one shoulder. Thank you for this Q&A.
(10) 2.5mg pills is generally considered the highest oral dose (that's 25mg) but that's because it's likely to do damage to your GI tract at that high a dose. If >20mg is called for, you might be better off taking 15mg twice a week or getting it by infusion/injection. Good luck. I'm on 17.5 right now and I seem to have an equal number of side effects and positive effects, but my disease (autoimmune featured interstitial lung disease) is hard to treat and I have no doubt whatsoever that MTX is keeping me alive. So I complain about MTX but I think it is worth it. Strangely enough, it relieves my pain but keeps me awake. I had to go on ambien because of it.
- Methotrexate Information for Consumers
- Methotrexate Information for Healthcare Professionals (includes dosage details)
- Side Effects of Methotrexate (detailed)
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