I have been on methotrexate 20+ years. Is this safe?

Hi Jab-Jam. Having recently started on methotrexate myself over the last several months, I've taken the opportunity to do some research into this medication. What I have found that may help answer your question is that studies have shown that generally methotrexate is well tolerated for use in the long term. Having said that, I am assuming your doctor is regularly testing your liver functions and that these tests are coming out satisfactorily. I totally understand that 20 years is a very long time to be on such a strong medication. If you have concerns about this, I would highly recommend you have a discussion about this with your physician. Let him/her know some of the side effects you seem to be experiencing now and discuss your general feelings of unease with being on this medication for such a lengthy period of time. Ask your doctor to elaborate on how the benefits of staying on this medication outweigh any potential risks. You have a right to understand their thinking on this matter so that you can make an informed decision. If you find out anything you'd like to share please post back here. Good luck and good health to you.

Just for those that are taking this, iT'S BEEN AROUND FOR MANY MANY YEARS AND THIS IS ONE OF THOSE MEDICATIONS THAT AS LONG AS THE DOCTOR DOES REGULAR TESTING YOU SHOULD BE JUST FINE THERE REALLY ARE NOT MANY OPTIONS TO THIS MEDICATION FOR THE PATIENTS THAT REQUIRE IT AND AS LONG AS IT IS DOING WHAT IT SHOULD BE DOING YOUR FINE WITH THE BLOOD TEST. And any doctor using this knows that very well. But there really is no other options to control the problems you have it is used for many things and they would not use it if the benefits did not outweigh the long term effects.