... thighs and calfs cramp so much I cant walk. Its there something else I can do even when I take them at different times. please help
You should talk to your doctor. You may need to review your dose of mestinon. This is taken from the below side-effect link for Mestinon.
"... Adverse effects that are generally associated with overdosage have included muscle cramps... "
See these links for a list of side effects for Triamterene and Mestinon :
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