Took one Mefloquine pill 250mg for prevention, never went to malaria area became too ill of mefloquine started 48 hours after the pill. Still suffering severe reaction after 6 months, no improvement. Vertigo, anxiety, dizziness, hearing loss in a way, visual problems, depression, suicidal thoughts, heart palpitations, mussle weakness and pain, lost feeling on skin, numb feet hands. can sleep just 6 hours by myself now after 5 months of insomnia. Severe cognitive problems, always on a trip. Use Ativan to try to cope through a day. Now I want explanation on this and how long does the average severe effected person takes? Had no history before and was a healthy 45 year old lady.