I stated taking the generic for Zoloft and trazodone for anxiety about two weeks ago and I noticed that I recently wake up with the worst anxiety sometimes. I did a guided meditation last night and this morning and I woke up a couple of hours after both with really bad anxiety and I'm not sure if the meditation caused it or if the medicine's not working. Because I woke up two days ago with bad anxiety also. How would I know if the meds aren't working? Because last night when I did the guided meditation I fell asleep without taking my trazodone and woke up at like 1AM with anxiety but I've taken the trazodone that late before without anxiety. I'm not sure if its the meds or not. My therapist said anxiety spikes are normal but this often?