It seems that every drug I've taken for my panic disorder and bipolar disorder cause weight gain. I took a "medication vacation" for a year, and my weight decreased dramatically. After years of taking medications for my disorders, my weight gain has put me in the obese category. The only time I could lose weight was when I developed breakthrough mania for 8 weeks without treatment. Side effects such as nausea and lack of appetite prevent me from overeating, yet I still gain weight, so it has to be the medications. I have developed all of the problems associated with obesity, such as high blood pressure, type II diabetes, and elevated cholesterol, for which I have to take more medications to keep those levels in check. I have a drug tray with all of my medications that looks like I started a pharmacy. Do I have to trade off weight gain for mental health management? Has anyone else experienced these problems?