... antidepressant & moodstabilzer (I think I need something better for the mood stabilizer) , but I still get extremely moody right before that time of month. Effexor xr is what I take for the antidepressant & is said to help with pmdd as well. Can the meds be adjusted just for one week each month or some type of med to take withmymeds during that time?? I seriously feel psychotic sometimes during thattime. The menstrual cramps are troublesome too.