My 12yr old son is taking desmopressin for bedwetting. He has been on it for almost a year. He is taking 3 tablets@.02mg/night. He was taking 2 tablets, but it wasn't working. Now his dr. has upped his prescription to 3tablets/night. I am worried that this might be too high of a dosage for a 12yr. old. Sometimes 3 tablets don't even work though. Also, I am wondering if there is any long-term affects from desmopressin. I tried to find out information online but couldn't find any information on it.
Here's what this site has to say about your question.
Primary Nocturnal Enuresis: Desmopressin acetate tablets have been safely used in pediatric patients age 6 years and older with primary nocturnal enuresis for up to 6 months. Some patients respond to a dose of 0.2 mg; however, increasing responses are seen at doses of 0.4 mg and 0.6 mg. No increase in the frequency or severity of adverse reactions or decrease in efficacy was seen with an increased dose or duration. The dose should be individually adjusted to achieve the best results.
Hello kimdbrooks, this is a bit late, but I just came across your post looking for my own answer. Two of my three children (now in their 30's) were wetters. My family tree has several wetters in all generations, including myself. I kept my kids on DDAVP (desmopressin) until it worked. My son was on it for about a year, my daughter was on it for about 2 years. When one of them had accidents then I would continue the dosage again for another 3 months without stopping. At the back of your brain is a hormone that tells the brain when you need to get up and potty... in night wetters, that hormone is not produced by itsself. DDAVP does that job. I started with DDAVP myself at age 40, and now at my age (old) I have decided to discontinue it purely because of the cost. I am on my 3rd week of weening myself off and so far no problem with day or night wetting.
When you try to take your child off of DDAVP start with lowering the dosage instead of stopping it completely along with NO, absolutely NO beverages after 7 pm. I also noticed over the years that watermellon and fruit juices caused wetting no matter what dosage. And the juice from Schwanns is the worst of them all. That drink would cause wetting 3 times a night in all of us while we were on DDAVP. Also, when my kids had a large glass of milk at supper time, again, there would be wetting. Since your 12 year old still has accidents when the dosage is lowered, be sure to have the doctor do all testing for possible physical problems. I have had no side effects with being on the med for 20 some years, and going off of it has been very positive. I am not a health professional, I can only tell you what I did and would do again. I have 3 wetters of my 11 grandchildren. As soon as they are of proper age they too will start desmopressin. A child does not need any more challenges to their self-esteem then is necessary. Sorry for rambling on about so much... forgive me! I hope this gives you a little insight into my life as a wetter.
Watch your child for a few days after giving this medication. Our dr. Told us if is very safe, so we sent him off to sleep away camp. He drank a lot at camp (which we told him to do). Ddavp causes the body to hold onto water, when he increased water intake, his sodium levels dropped. If sodium levels become too low, brain seizures can occur. We almost lost our child because of complacency with this medication.
- Desmopressin Information for Consumers
- Desmopressin Information for Healthcare Professionals (includes dosage details)
- Side Effects of Desmopressin (detailed)
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