I'm wondering if other ssri's were tried before zoloft became their number 1. I'm wondering if paxil was tried and what was it about it that did not work vs. zoloft.
I was first prescribed Zoloft as it is the most middle ground med out there, or at least quite a few seem to think so. I found the medication to work, but due to getting so tiered on it as well as sexual desires being eliminated, we tried several others before finding that pristiq worked well for me. After a period of time it had stopped working, and then moved on to cymbalta. When I lost my job I no longer could afford the med. Went back to zoloft and oddly no longer had the original side effets!
This is my story and everyone reacts differently.
I tried a myriad of SSRI anti-depressants prior to starting Zoloft, including Paxil. I am now a 36 y.o woman, and the time period during which I tried all the comparable SSRI's was between ages 19-30. Ultimately, the outcome was that all SSRI's were too stimulating. The negative side effects outweighed any positive benefits. I too have been diagnosed with PTSD. For those of us with anxiety issues combined with depression, finding the right medication can be a struggle.
My last experience with Zoloft resulted in my first (and only) in-patient stay in a psychiatric ward. I had been taking the Zoloft for appx. 3 weeks. 4 days after the Zoloft was discontinued, I was fine. They explained the Zoloft triggered a "manic episode" which led to my needing hospitalized. It was terrifying. The hospital then set forth with putting me on meds for bi-polar disorder (!) although this was a one-time, isolated incident which went away promptly when I discontinued taking Zoloft. The bi-polar med's side effects were awful (as it was not a proper diagnosis)- I am already a subdued person, so I didn't need any meds to further flatten my moods. Many professionals agree its possible that the over-stimulation caused by Zoloft can cause a singular manic event in the course of one's lifetime. I've since been evaluated and cleared of the diagnosis of bi-polar disorder by 2 independent psychiatrists. Consequently, I've avoided taking SSRI's since (that was back in 2004). Also, I've noticed there's currently a class action law-suit in the works against the makers of Zoloft so consumer safety is of concern. However, I do need to find a medication to help with recurring depression combined with anxiety disorder. I'm hopeful something can help.
That said, when I was younger- appx 20 y.o.- I did respond favorably to Zoloft without negative over-stimulation. So Zoloft was my "#1" for that brief period and was what I would consider THEN to be most helpful, in hindsight. It did have a "poop out" effect as the pysch called it, so the dosage would need raised regularly to continue as therapeutic. Eventually I was switched to another SSRI because the Zoloft ceased being effective. As I age, my nervous system has less tolerance for stimulants - be it Prozac, Paxil, Zoloft or even a just a latte. Of all the SSRI's I tried during those years, Paxil was one of the least over-stimulating. But it too was still too much.
I hope this has been of some help to you. It can take months or even years of feeling like a "guinea pig" before finding the medication or therapy that works best for you. Hang in there and make sure you've got family or close friends who are aware of your situation and who are there to support you. I'm grateful I did back in 2004! Best wishes to you.
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