I take 500mg a day and have several bothersome side effects, like impotence and pacing, though the benefits of the drug have had a positive effect on my life. I am only 44.
I used to take Thorazine (sadly am not allowed to anymore due to contra-indications) but only 100 mg/day. I usually only took it for 6 month spells mostly but was not bothered by any side effects, if anything, it improved my sex life and mental function of course. I did find I built up a tolerance to it quite rapidly however so found the breaks useful.
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