Frank as said earlier your lucky most the time the side effects are the first thing to kick in and as far as when well it kick in that well be known by the blood test the doctor takes as it says here in this copy and paste with hormone there really is no for sure time..Your symptoms may become temporarily worse as your hormones adjust when you first start using Lupron. For best results, keep using the medication as instructed by your doctor. Your condition should eventually improve with continued use of leuprolide.So that is what it says about when it kicks in Chuck1957 When you have to go in for a blood test that would be a good question for the doctor...
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