i stopped getting the shots since the above had no effect on rising p s a. down the road i'm taking zytiga with prednisone my other dr told me if the number drop low stop taking if for awhile when the numbers increase then go back on it. have had been successful. now new oncologist is mad because i stop the shots, and was even madder because my other oncologist had a different treatment of stopping it. true my psa after 8 yrs is 2.77 but its climbing and i'm confused