My friend suffered a Traumatic Brain Injury 19years ago. He has shown signs of mental decline the last couple years looking like dementia. He recently lost his mother who has been his sole provider and had to be put in a nursing home. He was having agitation and cursing out his care providers when he first moved in which is out of character for him. He has been showing the signs of dementia though but I think the outbursts were related to all of the recent losses and having his world turned upside down. They put him on seroquel 25mg at 8am and noon daily. He seems over-medicated and has difficulty talking without falling asleep and slurring his words. I had suggested that they consider lowing his dose or spreading out the times it is given. Thanks for any info you can give me.