If you work on total clearance of active metabolites as well then it can take about 165 hours (5.5 x elimination half life (30 hours used) for all of it be totally cleared.
Excretion: Lipitor and its metabolites are eliminated primarily in bile following hepatic and/or extra-hepatic metabolism; however, the drug does not appear to undergo enterohepatic recirculation. Mean plasma elimination half-life of Lipitor in humans is approximately 14 hours, but the half-life of inhibitory activity for HMG-CoA reductase is 20 to 30 hours due to the contribution of active metabolites. Less than 2% of a dose of Lipitor is recovered in urine following oral administration.
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