Hi I'm Franklyn. I was diagnosed in 2010 and was on pentasa and prednisone for a long time. I couldn't wean myself off it as I experienced a bad flare attempting to do so. Last Nov 2014, my doc got me on remicade. Helped me for 4 months until I had a bad allergic reaction and was instructed to stop. Now I'm on humira, I just took the first 160mg starter dose, felt great afterwards but had two bowel movements at night which were non bloody. Had two bowel movements this morning again. Is this medication not effective or it takes awhile to kick in. Need helpful answers