I have PMDD and have had it for several years now. I was never like this and it’s very hard to deal with. After getting off Zoloft due to weight gain, my doctor switched me to Trintellix. I didn’t see much of a different with the PMDDon this. My doctor suggested Prozac 20 mg to start off. It has been 5 weeks and I still feel real bad. I’m wondering if this dose is low, or if the Provigil 200mg may not be helping with the PMDD. I’m tired of this illness.