I've been on Cymbalta for nearly 3 weeks now for major depression, and haven't really noticed any change at all. I know they say it could take 4-6 weeks for maximum effectiveness, but I'm unclear what that means? Does this mean I won't see changes at all until 4-6 weeks, or should I be noticing gradual changes sooner than that? I've been really bad for 4 straight months and I'm just desperate to feel better.
I understand how desperate you are to feel better. I too was in a dark place when I started Cymbalta. I began to feel better in the 3rd week and then about a year later we confirmed that I needed to add something to it. Please hang on and give it another week to begin kicking in so you notice it. If you haven't already contacted your practitioner to let them know it's taking it's sweet time, you may want to do that and let them know that if you're not improving in the next week you would definitely like to try something else. They only have us and how we can't get out of bed and can barely force ourselves to be around the people we need to be around. Be very specific with your reports... it also helps to quantify if the med is helping.
Please hang in there and good wishes to you.
"Sleep, energy, or appetite may show some improvement within the first 1-2 weeks. Improvement in these physical symptoms can be an important early signal that the medication is working. Depressed mood, anxiety, and lack of interest in activities may need up to 6-8 weeks to fully improve.
Duloxetine (Cymbalta) | NAMI: National Alliance on Mental Illness"
Best regards and try to be patient... these medications just take time to adjust your metabolism. It'll be worth the wait, you'll see.
- Cymbalta Information for Consumers
- Cymbalta Information for Healthcare Professionals (includes dosage details)
- Side Effects of Cymbalta (detailed)
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