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How long does your body take to get use to Depo-Provera?

Responses (2)

Marvell 15 Dec 2012

Everyone is different in what they experience with Depo Provera. Some people have no problems from Day 1, for some it may take a month or two to get used to it.

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https://www.drugs.com/comments/medroxyprogesterone/depo-provera.html

LousArk 15 Dec 2012

My experience was that it actually took a long time. My bleeding was irregular for about 6 months, until it completely stopped. During that time it could be heavy, initially. After that, I never had any bleeding or spotting, unless I was late for my injection.
Occasionally, I would bleed a week or two before the injection was due, & so the Depo would be given early, which tended to settle things down again.
Hope that helps x

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