I am having surgery but surgeon won't operate until I have a negative urine for nicotine.
What sort of nicotine exposure did you have? Smoking? Patches? Etc.?
Excreted in urine mainly as metabolites (70–90%) and as unchanged drug (10–30%).
Biphasic;12 terminal half-life averages 2 hours (range: 1–4 hours).
Following removal of a transdermal system, apparent half-life averages 3–6 hours.
If we took the elimination half life of maximum value i.e. 6 hours, the nicotine should be out of your system in approximately 33 hours. (it takes 5.5 x elimination half lifes for the medicine to be totally cleared from ones system, provided the patient is healthy and doesn't have any renal or hepatic dysfunction.
- Nicotine Information for Consumers
- Nicotine Information for Healthcare Professionals (includes dosage details)
- Side Effects of Nicotine (detailed)
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