... ADL's even doings thing like getting dressed is a battle and not really having a life. I'm not bipolar so I'd imagine a lower dose would work if it was to work. I do have mood swings and outbursts of anger to the point of breaking things and punching holes through the walls sometimes. I currently take Remeron 45 mgs, Latuda 60 mgs, Klonopin 2 mgs BID, Nuvigil 125 mgs (half a 250 mg tablet) prasozin 1 mg TID, metoprolol 100 mgs and lisinopril with HCTZ 20/25 mgs