I have unfortunately been suffering with LS for around 18months and use oestregen cream every other night and clobesterol cream around three times a week and find this keeps it under control. I recently purchased a book relating to LS and read that it could possibly cause vaginal cancer I realise that LS sufferers are more likely to contact Cancer in that area but what else can I do I really do need some help and preferably a cure!!!
Since its been quite a while since there was anyone asking about it, I went to the mayo clinic web site to see if there was anything new. They're saying that immune modulating drugs are being used, specifically tacrolimus or elidel.
I also checked for the carcinogenesis of clobetesol. Being a strong steroid cream, the big risk is systemic toxicity. I can't find a thing that it causes vaginal cancer, or any kind of cancer. Estrogen cream has a small possibility of cancer in that area.
I have found when you get those books the are pushing the agenda of the writer not always giving facts that are backed up. I once was given one on fibro, by a Dr who claims to be an expert. Half of what he said was a bunch of bull, to find the truth about a disease you need to talk to a few who have had it a while. Unfortunately since ls is so rare, that's a problem for you.
Clobetasol is the strongest steroid ointment made but is the drug of choice for LS. It should be used sparingly and as least often as possible (e g. 1x per week as maintenance) to remain symptom free, rubbed in gently but for 90 seconds. Having LS (especially when it is NOT treated with clobetasol) raises your risk of vulvar cancer, not vaginal cancer. It is not the clobetasol that raises the risk of cancer. The risk with using clobetasol is that it can cause too much thinning of the skin. Because LS causes thickening of the top layer of skin, so you want the clobetasol to do some thinning, warming the area with a warm bath before applying and then rubbing in gently but well, helps the medication to penetrate the damaged hard skin and get to the "basement" layer which needs fixing. But again, you need to use as little as you can to maintain. Good luck.
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