I can't answer that question but I will share my experience- i broke some bones in my back and I took Norco while on Lexapro and it seemed fine. i told the ER repeatedly about the Lexapro and he didn't seem concerned at all. But not sure about Percocet. I will say that my Mom was on dilaudid while on Lexapro when she had cancer, I don't think there is an interaction with ADs.
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