Hello there. I have been taking 5 mg of Lexapro for 7 weeks now and still feel depressed, and somehow slightly more depressed than I was prior. My pdoc wants to up the dose to 10 mg. I just get a strong sense that this drug is not going to work at all. How long do I wait before just weaning off of it and trying something else. Had major depression years ago and was successfully treated with Zoloft with full remission for 17 years. This depression is so different. It feels like there is something wrong with my brain. I don't cry or anything. Just so depressed in such a weird way.