Hi!, My wife is 30 years of age, we have two beautiful children, 11year old daughter and 6 year old son. She had some digestion problem thus the doc gave her Levopraid (LevoSulpiride) 50mg twice a day with SelanzSR 30mg once a day. She have been taking these for the past 3 weeks and now has noticed lactation. She is not pregnant.
does Levopraid (LevoSulpiride) cause lactation? as I read that Sulpiride is a strong stimulation of prolactin-secretion?
yes this can be due to levosulpiride, as it is an neuroleptic drug. It blocks D2 receptors, and so it does in the tubero-infundibular tract. That tract is responsible for regulating prolactin-secretion. By blocking D2 in that tract, you take away the inhibitory effect on prolactin secretion, which, as a result may increase. Clinically, lactation may be one of the symptoms as a result.
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