Can you explain the function of the Topamax? I am experiencing weight gain with each one of these anti-depressents. Seroquil worked the best for me; however, I also gained the most quite quickly on that med. So, I tried Latuda. At first, I had a supressed appetite... and weight decreased from the "gain" a bit. However, now my weight is at a standstill, my appetite has slightly increased, i workout frequently, and i eat a moderately healthy diet. Does Topmax prevent the weight gain?