I've been on Latuda ( currently 80 mg).
I've doubled my Vyvanse to the daily max, and also take Adderall XR 40 mg ADHD in addition.
I barely my feel the ADHD medication at all, and it worked great at 35 mg.

Also I used to use Medical Marijuana, but same issue, I can smoke the oldest dead heads under the table, and I don't feel it at all.

Why does Latuda have this effect?