I’m currently taking 120 mg in the morning and have added 30 mg in the evening every other day. Have started on Cymbalta slowly 5 months ago after a severe depression. I reached 120mg every morning without side effects. After 8 weeks I suddenly felt the difference no bad bad thoughts, more functional, more connected. This happened at the middle of July. However that was ... I still feel the same... I’m not back to my normal self though. My doctor tried 150mg all together in the morning and after 3 weeks I went crazy—over stimulated. I went back to 120 and after a week I felt better. I’m so hopeless. I still feel disconnected. I think that’s it. I will leave with the fog of depression for the rest of my life. I have added 30mg to 120, but I take 30mg in the afternoon every other day. For two weeks haven’t had any improvement nor side effects. I’m a young working mother with two small children. This is ruining my life completely. After trying so many others I had so much hope with Cymbalta since I didn’t have any of the terrible side effects people are talking about. My doc wants to add 100 options to make me feel better... gabatine, lithium even though I’m not bipolar, ketamine and i don’t remember what else. I have lost hope... I feel more for my children that don’t have the real mom rather than for myself. Yes, I exercise I eat healthy I think positive I try to laugh but no the fog is there. The clouds are all over me.. Someone told me take 60mg in the morning 60 in the evening but I don’t have side effects of taking 120 in the morning plus the 30 in the afternoon.. I wish for a miracle after struggling for 8 years. Please help me
Hi, Antonia! I'm not sure if your doctor suggested an add-on like Abilify or Rexulti ~ about 2/3 of patients don't get full control on an antidepressant alone. These add-ons act in their own right as sort of a mood stabilizer and booster the effects of your AD. Another option might be Latuda for unipolar depression.
**The safety of doses above 120 mg/day has not been adequately evaluated. Periodically reassess to determine the need for maintenance treatment and the appropriate dose for such treatment.**
If your prescriber is a GP or PCP I'd also suggest a second opinion from a licensed psychiatrist.
Best regards, Wildcat
Hi. I also have struggled with this depression for years, & do all the same things u do! However, two other things have helped me. The first one is, yes, taking half my dose at night, & half in the morning, really did make a difference! It keeps my body more level, therefore avoiding any really bad times (like u said, u take an extra 30mg in the afternoon/evening. U could try using this time as ur night time dose, & the other half of ur dose in the mornings). The 2nd thing I changed is my diet. I have ALWAYS eaten healthy. NO ONE ever thought my diet was affecting anything. But just knowing how important food is... I made a change by myself... & it has worked! I cut out gluten. It was SUPER hard at first, & it IS more expensive (even if only in the extra time it takes). But there - LUCKILY - are tons of options now, & some great budget cookbooks on eating gluten-free for less. Once u get the hang of it, it does get easier! I noticed some changes within days, more within 2 months, & even more after 6mo. NO BRAIN FOG. DESIRE FOR LIFE RETURNED. DEPRESSION ALMOST NON-EXISTENT. CLEAR THOUGHTS, AND LOOKED FORWARD TO EACH DAYS ACTIVITIES. NO HIDING IN BED ANYMORE. I actually cared about everyday things. The only thing is, no cheating. When I thought I was "cured," I chowed on an entire loaf of gluten-heavy bread over a weeks time. It took two whole months to start feeling better again! Unfortunately, because of money, I have had months where I had to eat what was given to me. BUT the good thing is that I have tested, & re-tested, the effects of gluten on brain fog, desire, & depression. What we eat DOES affect our brain, & I definitely believe gluten is the devil! I obviously don't know if u have gotten any better since u wrote ur question, but I highly recommend cutting gluten completely out of ur diet! There are so many options now, it's totally doable, even with young kids! AND they will most probably have a "totally normal" mom! I know it's the first thing in almost 30 yrs that's helped me (in addition to Cymbalta)! Good luck & God bless.
- Cymbalta Information for Consumers
- Cymbalta Information for Healthcare Professionals (includes dosage details)
- Side Effects of Cymbalta (detailed)
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