... to go to the hospital. I have suffered from depression on and off since I was 17 (now 36), but never like this. I was taking Prozac and Trazadone, and had Lamotrigine added on Monday. I have been taking it at night with my 100mg of Trazadone, and I have been really restless at night (something I never was when taking just the Trazadone). When do people usually take their Lamotrigine?