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Lamictal - Can you take Lamotrigine with Gralise (gabapentin)?

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coloresue 23 Jun 2015

There's a minor reaction between the 2 drugs which only your Dr. or pharmacist can explain. Your pharmacist lacks your personal history. Results from this site:
"Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

"For clinical details see professional interaction data: Lamotrigine may increase the plasma concentrations of renally excreted drugs that are substrates of OCT 2. Lamotrigine inhibits OCT 2 in vitro. The clinical significance is unknown."

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