I have epilepsy. I have been on Dilantin for over 15 years. My doctor has switched me Lamictal about two months ago for my seizures. I'm currently on 450mg a day but will be upgraded to 500mg. I've noticed my moods have changed. I've been depressed and have a loss of appetite (reported side effects of Lamictal). I've been told that it is common to prescribe Lamictal with an anti-depressant. If anyone had to combine Lamictal with an anti-depressant to control seizures, did you stay on the anti-depressant for a long period of time?