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Konakion - dosage in case of prolonged PT?

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suzanne66 17 Aug 2009

I am unsure of a few important details so have found these detailed dosage instructions for Vitamin k1 Konakion)

From:https://www.drugs.com/pro/vitamin-k1.html

Vitamin K1 Dosage and Administration
Whenever possible, Vitamin K1 Injection (Phytonadione Injectable Emulsion, USP) should be given by the subcutaneous route.

Anticoagulant-Induced Prothrombin Deficiency in Adults

To correct excessively prolonged prothrombin time caused by oral anticoagulant therapy—2.5 to 10 mg or up to 25 mg initially is recommended. In rare instances 50 mg may be required. Frequency and amount of subsequent doses should be determined by prothrombin time response or clinical condition (see WARNINGS). If in 6 to 8 hours after parenteral administration the prothrombin time has not been shortened satisfactorily, the dose should be repeated.

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