what r all the side effects to the usage, short or long term
Arthrotec (diclofenac/misoprostol) is a prescription medication approved to treat the symptoms of osteoarthritis and rheumatoid arthritis in people who have a high risk for stomach or intestinal ulcers from using nonsteroidal anti-inflammatory drugs (NSAIDs). It contains two different medications: Diclofenac sodium (Voltaren, Voltaren-XR) and Misoprostol (Cytotec).
The diclofenac component is an NSAID. It can help relieve symptoms of arthritis, such as pain and swelling. The medication will not cure arthritis, however, nor will it slow down the progression of the disease.
Diclofenac can increase the risk for peptic ulcers (stomach or intestinal ulcers). Peptic ulcers occur when acid in the digestive tract eats away at the lining of the small intestine or stomach, causing a sore or lesion. The regular use of NSAIDs, including diclofenac, can irritate and weaken the lining of the small intestine or stomach, allowing acid to reach the wall of the stomach or intestines.
If an ulcer occurs in the upper part of the intestines, it is called a duodenal ulcer. Ulcers that occur in the stomach are called gastric ulcers. Gastric and duodenal ulcers can lead to serious complications, including internal bleeding.
Misoprostol, the other medication contained in Arthrotec, is a prostaglandin. It helps reduce the risk of ulcers from NSAID use. Because Arthrotec contains misoprostol, it may be a good choice for people who have a higher-than-normal risk for gastric and duodenal ulcers and complications from ulcers. This includes people who: Have had a peptic ulcer, or stomach or intestinal bleeding in the past; will be using NSAIDs for an extended period of time; smoke; use alcohol; are older in age; have poor general health; use other medicines that increase the risk for ulcers or bleeding.
Arthrotec combines two different medications that work in different ways. Diclofenac sodium, the pain-relieving component, works by blocking the production of prostaglandins, which are hormone-like substances in the body that cause inflammation and pain. By blocking the production of prostaglandins, diclofenac can reduce pain, inflammation, and joint swelling associated with arthritis.
Misoprostol, the other component, is a type of prostaglandin. It works by decreasing stomach acid secretion and protecting the lining of the stomach from stomach acid and other harmful substances.
However, for more info do seek advice from the doc/pharmacist who prescribed the med.
Take care, best wishes!
Hello mett, & welcome to the site. My friend Rajive has answered what this medicine is for & what is does etc,,, but wanted to also add that after hearing about it here on the site decided to try it myself as I cannot tolerate any NSAIDS at all, & was hoping it was the answer for my osteoarthritis which is very severe. Well, unfortunately, the very first dose gave me severe pain & crampin in my stomach. I gave it two doses, & I was bent over in stomach pain. Just a warning that if you decide to try it for this, & also have trouble with NSAIDS, please ask your doctor for a smaple to try or just get a couple of days worth of your prescription as you too may have trouble with it. If you don't you cn always get the rest of your presecription. I had to throw out a whole months supply. Just my thoughts... Mary
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