I went off Dilantin and had problems with seizures. I was put on Keppra XR starting at 1500 on way to 3000. I always took at night in one dose. Minor seizures persisted. I was in raised to 4750 and had bad side affects. Eventually I learned that no more than 1500 mg should be taken at once. I split throughout the day and that helped. I now, after 3 years of semi-annual adjustments, take 2000 mg total with 150 Vimpat. Half AM/ PM. This is tolerable with minimal side affects.
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