... day usually. i usally notice wds well before 24 hours has past. runny nose, sneezing, leg pains etc. i have an appointment with a suboxone doctor tommorow and its been 30 hours since ive had my last roxy and the only symptoms im having are the runs slight joint/muscle pain and cravings. no dialated pupils sneezing runny nose or severe rls yet. whats going on?