that supposedly there is a new anti depressent out with painkilling properties to it, does anybody know what this could be?
Hi Aaron. I found this article after talking with the pharmacist. This may be the medicine! Cymbalta...
"Nov. 5, 2010 – A drug used to treat depression, anxiety, fibromyalgia, and diabetic neuropathy has been approved by the FDA for a new use -- to treat chronic musculoskeletal pain, including pain caused by osteoarthritis and chronic low back pain.
The drug is sold under the brand name Cymbalta (duloxetine hydrochloride) and is manufactured by Eli Lilly and Co., a major pharmaceutical company based in Indianapolis. Chronic low back pain is one of the most common forms of musculoskeletal pain, and finding an effective treatment can sometimes be challenging.
The approved dose for chronic musculoskeletal pain is a 60-milligram capsule taken once a day, swallowed whole; it does not have to be timed with meals.
"Up to three-quarters of the population experience chronic pain at some time in their lives," Janet Woodcock, MD, director of the FDA's Center for Drug Evaluation and Research, said in a prepared statement."This approval means that many of those people now have another treatment option."
Clinical trials showed that taking Cymbalta significantly reduced chronic pain, compared with a placebo. More than 29,000 patients used Cymbalta in clinical trials, including people with osteoarthritis and chronic low back pain.
The most common side effects among Cymbalta users were nausea, dry mouth, insomnia, drowsiness, constipation, fatigue, and dizziness. There were serious side effects as well, including liver damage, hives, rashes, swelling in the face, pneumonia, depressed mood, and suicidal thoughts and behavior. These more serious side effects have occurred in less than 1% of patients taking Cymbalta.
Since its approval in 2004, an estimated 30 million people have used Cymbalta"
I currently take 120mg of Cymbalta for my fibro pain as well as my depression, anxiety, and ptsd (which might be the cause of the other two). It helps a bit with the pain - but really, not a whole lot, but a bit. If I have to take an antidepressant, it might as well be dual acting. It doesn't make me tiered like some do, and it helps a whole lot more with the other symptoms, more than did Pristiq, a drug that either my system got used to, or the symptoms just got worse, and you can't really adjust that med at all, unlike the others...
Regarding the negative side effects, supposedly there have been very very rare reports of liver damage, and realistically, you shouldn't be worried about them, unless you drink excessively on a daily basis. It doesn't have anything near to the damaging qualities that tylenol has - so according to the info that I've been fed (they've been wrong / lied to me before), it realistically is a harmless drug to take long term. I now trust my doctor (unlike before, as he's helped me out a ton with insurance, samples, and getting by with no job), and have agreed to take the med as was mentioned above.
Another set of drugs that really help nerve pain allot are the TCA's. I think that there's about three of them that are commonly used to treat pain. They worked better for me, however, I got some strange side effects from them, and wasn't able to take them (the left arm felt like it was asleep, and the fingers burned, - the moment that the drug was out of the system, everything went back to normal... strange).
I do have to say though, that I didn't respond well to the Lyrica, as it made me feel tiered and sick at the dosage that I would have needed (400mg), and the Cymbalta hasn't really done any vast wonders for me either. Tramadol helped a little as well, but stopped that one due to the potential for addiction (benefit vs. harm ratio didn't make sense), but the Methadone knocked the pain out completely (yes addictive, but helpful enough that it's justified - the benefit vs. harm ration made sense for my situation.) So, that's just me, as apparently both Lyrica and Cymbalta have done wonders for many many people before, as everyone reacts differently to these meds.
Hope that this is of some help to you!
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