This is what the Interactions Checker had to say on the 2 meds:
Applies to: metoprolol, aspirin
High doses of salicylates may blunt the antihypertensive effects of beta-blockers. The proposed mechanism is inhibition of prostaglandin synthesis. Low-dose aspirin does not appear to affect blood pressure. In addition, beta-blockers may exert an antiplatelet effect, which may be additive with the effects of some salicylates. Metoprolol may also increase aspirin absorption and/or plasma concentrations of salicylates; however, the clinical significance of this effect is unknown. Data have been conflicting. Until more information is available, patients who require concomitant therapy should be monitored for altered antihypertensive response whenever a salicylate is introduced or discontinued, or when its dosage is modified.
For more info please do seek medical advice from the doc/pharmacist who prescribed the meds, hope the info helps? Take care, & have a nice week & safe week end!
- Aspirin Information for Consumers
- Aspirin Information for Healthcare Professionals (includes dosage details)
- Side Effects of Aspirin (detailed)
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