I've been through a few dozen medications in many combinations over the past 15 years, and they're all side-effects and no effects. Now that I need to take NSAIDs (another problem-prone class of drugs) for arthritis, I'm more worried than ever about mixing in these ineffective drugs for my PTSD symptoms. I've been taking Cymbalta 60 mg for a year or two, dexedrine or Provigil for daytime hypersomnia, diclofenac for osteoarthritis, and clonidine for startle and migraine. Nothing stops the depression or flashbacks, the other meds usually help their respective problems, and you can see why I'm concerned about my liver. I'd prefer to take fewer Rxs, and take Rxs that actually work.