She appears to have major tantrums 30 minutes after her doseage. She has been on both for 2 years and all her bad behaviors or screaming, aggression and major tantrumming are back. When I missed her morning dose, she ended up having a good day. I don't know what to do. She is 10 years old and has autism. She has also gained 30 pounds in 2 years with no significant change in diet except she eats healthier now.