I had been on Celexa 20mg for many years. It just seemed to stop working. I don't have major depression,but it is there, and I do have bouts with anxiety. After speaking with my new Dr., because of new great insurance, we switched me to Effexor XR. He started me out at 75mg which I read is the normal starting, he said he'd like to see me after about a month on this dose as it is roughly equal to the 20 mg of Celexa. My only concern is that I've also read that Effexor XR is simply acting as any other SSRI at 75 mg or less and you only get the SNRI effect at 150 mg. I'm not trying to find a problem that isn't there, just concerned that for the next month I will be not seeing any benefit.