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Is it medically aproved to use mucolytic agents for cystic fibrosis?

Responses (1)

suzanne66 26 Oct 2009

Mucolytics dissolve mucus in the lungs or intestines, making the mucus thinner and less sticky.

However, these drugs are not used very much because they can irritate the lungs. Usually DNAse enzyme replacement therapy is used . The medication dornase (Pulmozyme) contains an enzyme that thins the mucus and makes it easier to cough up.


williamhoh 12 Oct 2017

With all due respect, enzyme replacement medication is Creon or Pancreas. It's protease/lipase that aids in digestion of proteins and fats given that most people with cystic fibrosis have little to no pancreatic function.

Pulmozyme is a DNAade and is considered a mucolytic agent. It's routinely used in most every patient with CF. it is made a tremendous difference in the life expectancy and quality-of-life for people with CF. I practiced medicine prior to Pulmozyme and after its introduction. Pulmozyme is a wonderful medication. Son inhales Pulmozyme every single day . It can be somewhat irritating, but some irritation is much preferred to recurrent pneumonias with hospitalizations free discount card

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