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Is augmentin safe during pregnancy when used with zophran and phenergan?

Responses (1)

suzanne66 13 Jun 2011

Augmentin and Zofran have both been assigned to pregnancy category B by the FDA. This means that animal studies failed to reveal any evidence of teratogenicity and there are no controlled data in human pregnancies.
They both should only be given during pregnancy when a need has been clearly established.
Phenergan (promethazine)has been assigned to pregnancy category C by the FDA. Several retrospective studies have suggested that there is no increased risk of congenital malformations in humans with the use of promethazine in pregnancy. Promethazine has been shown to impair neonatal platelet aggregation when given during labor. There are no controlled data in human pregnancy. It should only be given when the benefits outweigh the risks.
https://www.drugs.com/pregnancy/promethazine.html
https://www.drugs.com/pregnancy/ondansetron.html
https://www.drugs.com/pregnancy/amoxicillin-clavulanate.html

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