It depends on the size of the individual but a "normal" dose of methadone would be 10mgs per 120mL so approximately half a milligram in one liter would not be an overdose. I do hope I have understood your question correctly. To read more about dosages for methadone, you can go to:
- Methadone Information for Consumers
- Methadone Information for Healthcare Professionals (includes dosage details)
- Side Effects of Methadone (detailed)
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