... Provider wanted me to start medication, januvia 100mg, then to metformin er 1000mg, a1c remained the same under 7. In october of 2014 changed my diabetic medication to invakana, after 3 months my a1c 8. 6. Blood sugars over 250 every day. I stopped taking the invakana and resumed the metformin, my sugars are down but still over 200 even with 8 to 12 hour fasting. Has anyone else had this issue?