It's hard to address your first question as to "invented" methadone. My best guess would be addiction specialists (MD's) and/or pharmaceutical companies. The when and what's it used for was originally to come off of heroin. Seems to take a long time. Addiction is a disease like alcoholism. It takes over your entire life, when all you do is spend your time worrying about how to get some, the euphoria while using... ruined many a life, and heroin killed a lot of people, be it OD or hepatitis or AIDS, etc. Babies were born addicted to heroin. Was a major problem in the US, not counting all of the crimes associated with the dealers, procurement of the drug, murders, and every other crime you can think of. So methadone made its appearance on the scene. At last a way, a safe way to get off of heroin, not a pleasant life. Methadone keeps the junkies from going Thru wd's (withdrawals) but did not produce a high. Sometimes it works, sometimes not, depends on the person and motives and a myriad of other variables.
Now methadone is used in pain management at some facilities. Every doc has a comfort level as to which meds they will prescribe. It's a long acting pain med and doesn't have to be taken as frequently as some other meds.
You might want to Google methadone and see what info found online. For that matter, look under drugs a to z at this site got more information.
Good luck in your quest for knowledge,
Methadose, Physeptone, Heptadon, Phy and many other names) is a synthetic opioid, used medically as an analgesic and a maintenance anti-addictive for use in patients with opioid dependency. It was developed in Germany in 1937. Although chemically unlike morphine or heroin, methadone acts on the same opioid receptors as these drugs, and thus has many of the same effects. Methadone is also used in managing severe chronic pain, owing to its long duration of action, extremely powerful effects, and very low cost. Methadone was introduced into the United States in 1947 by Eli Lilly and Company.
Methadone is useful in the treatment of opioid dependence.
- Methadone Information for Consumers
- Methadone Information for Healthcare Professionals (includes dosage details)
- Side Effects of Methadone (detailed)
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