I have been having extreme discomfort in my knees using steps and when sleeping. Love to walk but sometimes that is somewhat uncomfortable. In the morning when getting up my whole body is still, including fingers until after I get moving. Vioxx years ago helped more than anything but was taken off the market. Since I have tried Arthrotec, Diclofenac, Naprosin and now Piroxicam. None of them have relieved the pain. I do have a heart condition -cardiomyopathy , have a defib and pacemaker. I also have mild asthma. I am now seeing a rheumatologist who has tried the naprosin and Piroxicam. I was wondering if there is anything else out there that I could try or discuss with him. I'm having difficulty sleeping also because my leg wakes me up just throbbing. Would appreciate any suggestions. Thank you.