"... Combining these medications may reduce the effectiveness of clopidogrel (Plavix) in preventing heart attack or stroke. The interaction is most likely to occur if you are using a higher dosage of lansoprazole (Prevacid) than recommended or if you are using it too frequently. If you have any concerns, your doctor or pharmacist may be able to offer suggestions on safer alternatives for stomach acid or ulcer while you are being treated with clopidogrel."
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