Adult onset Type I who has used Glargine for 10 years. Recently 3 new bottles of Lantus have not acted to maintain blood glucose appropriately. Short acting insulin still works well but am waking each night several times to monitor blood glucose and take short acting insulin as needed.
I have never heard of anybody becoming insulin resistance to the insulin, I guess it is possible just never heard of it. What I have heard of is that people sometimes, even Type 1's developing insulin resistance, but if that were the case, your short acting insulin would seem like it wasn't working as well either. I also have had friends that had gotten a bad batch of insulin both types. If we're to hazard a guess I would have to say that you got a bad batch of insulin. So make note of the batch number and contact your pharmacy where you get your insulin and tell them what's going on and I am sure that they can help you out also it would not be amiss to talk to your doctor about it also as you could be having some other issue that is interfering with your diabetes and you not know about it.
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