The Celexa is more for my Anxiety than anything and it does work perfectly in treating my Celexa. I am on Lamictal for my depression which I don't think works well for some reason the Celexa does little to treat my depression. I have tried Wellbutrin, Zoloft, Prozac, Abilify, Risperdal, Seroquel, Lexapro, and currently Lamictal for my depression and they barely touch my depression... any ideas of medications that work well for major depression
I was in the hospital for 6 months before the doctors found something to help my major depression. It was Manerix (Maoi) and Lithium. Nothing else worked. I am also sensitive to meds and the Lithium did give me the shakes a few months really bad but it worth it to be normal today. Those meds have given me back my happy life with my family again. I have been 6 years so far depression free. Now who would not like that?
Hope you find something that gets you out of the depression.
JennyLynn I hope you've found something that works since you posted in early May. But just in case, I'm wondering, of the meds you listed, were you given them individually? (Other than the Lamictal and Celexa.) Some have found that a combination of two or more is what it takes for the meds to be effective. On their own, they might not work well, combined, they might potentiate each other and you might have success. The doctor would know which ones to give together if you think that might work. Another idea I had was to possibly ask your doctor about trying an antidepressant in a different drug category. I see above that someone mentioned tri-cyclics, for instance. The meds you've already been given target certain neurotransmitters in the brain: Abilify, Risperdal, and Seroquel act on dopamine and seratonin (though in different ways- Risperdal and Seroquel actually diminish the action of those 2 neurotransmitters, while Abilify is supposed to balance them).
Zoloft, Celexa, Lexapro and Prozac act on seratonin (SSRIs), Wellbutrin acts on dopamine, and Lamictal acts on glutamate and aspartate. For the most part, anyway. Another class of antidepressant is called SNRI (seratonin norepinephrin re-uptake inhibitor). Effexor (venlafaxine) is one of those. Maybe affecting the norepinephrine will be the ticket? Something to consider asking the doctor about, anyway. Good luck and hang in there- this must be very frustrating.
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